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TFOS DEWS II iatrogenic report.
José Alvaro P Gomes1, Dimitri T Azar2, Christophe Baudouin3
1Dept. of Ophthalmology and Visual Sciences, Federal University of Sao Paulo/Paulista School of Medicine (UNIFESP/EPM), São Paulo, SP, Brazil.
The Ocular Surface
|July 25, 2017
Summary
Iatrogenic interventions, including medications and eye surgeries, can cause or worsen dry eye disease (DED). Further research and safer practices are needed to manage and prevent this condition.
Area of Science:
- Ophthalmology
- Ocular Surface Disease
Background:
- Dry eye disease (DED) is increasingly recognized, with iatrogenic causes becoming more prominent.
- Understanding the pathophysiology of DED is crucial for addressing iatrogenic factors.
Purpose of the Study:
- To provide a comprehensive report on iatrogenic dry eye within the TFOS DEWS II framework.
- To review various iatrogenic causes of DED, including medications, contact lens wear, and surgical procedures.
Main Methods:
- Literature review and synthesis of existing data on iatrogenic DED.
- Analysis of mechanisms by which interventions impact the ocular surface.
Main Results:
- Topical and systemic medications, preservatives (e.g., benzalkonium chloride), contact lens wear, and ocular surgeries (LASIK, cataract, etc.) are significant causes of iatrogenic DED.
- Surgical procedures can lead to DED through corneal nerve damage or postoperative treatments.
- Iatrogenic DED can negatively affect patient satisfaction, vision, and surgical outcomes.
Conclusions:
- There is a need for more epidemiological studies on iatrogenic DED risk factors.
- Development of less toxic medications, preservatives, and minimally invasive surgical techniques is essential.
- Early detection, appropriate therapeutics, and regulatory oversight are recommended for managing iatrogenic DED.
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