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Brucella Causing Liver Abscess in a Child with Selective IgA Deficiency
Devdeep Mukherjee1, Priyankar Pal, Ritabrata Kundu
1Department of Pediatric Medicine, Institute of Child Health, Kolkata, West Bengal, India. Correspondence to: Dr Devdeep Mukherjee, Uttara Cooperative Housing Society, 13, Broad Street, Kolkata 700 019, West Bengal, India. devdeep_dm@rediffmail.com.
Background:
Brucella has been known to cause pyrexia of unknown origin.
Case Characteristics:
9-year-old boy with fever and abdominal pain; multiple abscesses within the liver on ultrasonography.
Observations:
IgM Antibodies against Brucella were raised in his serum sample, and Brucella serum agglutination test was positive. Immunological work-up suggested selective IgA deficiency. Reduction in size following treatment with trimethoprim-sulphamethoxazole, amikacin and doxycycline.
Message:
Brucellosis should be considered as an etiology of liver abscess in patients not responding to conventional antibiotics.
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