Perinatal Chikungunya Virus-associated Encephalitis Leading to Postnatal-Onset Microcephaly and Optic Atrophy
Regina Ramos1, Rafaela Viana1, Alessandra Brainer-Lima1
1From the Department of Pediatric Infectious Diseases, Oswaldo Cruz Hospital, University of Pernambuco, Department of Neuropediatric, Oswaldo Cruz Hospital, University of Pernambuco, Department of Ophthalmology, Univision, and Department of Neuropediatric, Barão de Lucena Hospital, Recife, Brazil.
Abstract:
Chikungunya virus is capable of affecting the nervous system of children and adults. We describe a case of sepsis and encephalitis triggered by this agent in a newborn whose mother developed symptoms of acute infection 2 days before delivery. Consequently, the infant had severe encephalitis that evolved with postnatal-onset microcephaly, bilateral optic atrophy, epilepsy and cerebral palsy.
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