Reduction of heart rate variability in hypertensive elderly
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Published on: June 5, 2019
Paulo Evaristo de Andrade1, Joice Anaize Tonon do Amaral1,2, Laércio da Silva Paiva1,3
1a Laboratório de Delineamento de Estudos e Escrita Científica , Faculdade de Medicina do ABC , Santo André , SP , Brasil.
Insights
Elderly individuals with high blood pressure show reduced heart rate variability (HRV) and parasympathetic nervous system activity compared to healthy seniors. This study highlights significant differences in cardiac autonomic modulation between these groups.
Area of Science:
- Cardiology
- Gerontology
- Physiology
Background:
- Global aging population necessitates research into age-related health conditions like hypertension.
- Heart Rate Variability (HRV) is a key indicator of cardiovascular function, assessing autonomic nervous system activity.
- Limited research exists on HRV in elderly hypertensive patients compared to normotensive individuals.
Purpose of the Study:
- To compare cardiac autonomic modulation between healthy elderly individuals and those with hypertension.
- Investigate differences in HRV parameters indicative of autonomic function.
Main Methods:
- Study included 80 elderly participants: 40 healthy and 40 with hypertension (HBP).
- Collected anthropometric data, performed HRV analysis (time, frequency, and geometric domains), and administered the IPAQ questionnaire.
- Analyzed HRV parameters including pNN50, SDNN, RMSSD, LF, HF, RRtri, TINN, SD1, SD2, and the SD1/SD2 ratio.
Main Results:
- Hypertensive elderly showed increased MeanRR and a decreased SDNN compared to controls.
- Frequency domain analysis revealed a significant decrease in High Frequency (HF) power in hypertensive individuals.
- Geometric analysis indicated reduced TINN and SD2, with a significantly increased SD1/SD2 ratio in the hypertensive group.
Conclusions:
- Elderly patients with hypertension exhibit diminished heart rate variability.
- Hypertension in the elderly is associated with reduced parasympathetic nervous system modulation.
- HRV analysis provides valuable insights into autonomic dysfunction in hypertensive elderly individuals.
Introduction:
The elderly population grows globally every day, and along with it the incidence of high blood pressure also grows, following these data scientists seek tools to improve the health of this population, a widely used tool for assessing cardiovascular function is the heart rate variability(HRV), that is a mecanism that allows the investigation of oscillations in the intervals between consecutive heart beats (RR intervals). There are already studies on the autonomic nervous system in the elderly population, however, these studies investigated normotensive patients and there is little research in hypertensive patients.
Aim:
To compare the cardiac autonomic modulation between healthy elderly and hypertensive elderly.
Method:
The total sample was 80 elderly people- 40 healthy elderly and 40 elderly (HBP). Anthropometric data, HRV analysis and IPAQ questionnaire were collected. For the analysis of cardiac modulation data in the time domain (pNN50, SDNN and RMSSD) and frequency domain (LF and HF). The geometric analysis (RRtri, TINN, SD1, SD2 and SD1/SD2 ratios).
Results:
In the time domain the MeanRR index presented a HAS increase 832.35 ± 104.46 ms vs control 782.73 ± 112.78 ms (p = 0.040). In the SDNN, there was a 58.35ms decrease vs the SAH 43.15 ms (p = 0.030). In the frequency domain, HF decreased control 247.00 ms2 vs HAS 157.00 ms2 (p = 0.002). In the geometric, the TINN and SD2 in the HAS group decreased in relation to the control from 203.38 ± 80.26 ms to 161.83 ± 53.25 ms (p = 0.018) and from 71.95 ms to 59.40 ms (p = 0.051). The mean SD1/SD2 ratio showed an increase between the Control and SAH groups from 0.22 ± 0.10 to 4.09 ± 1.18 and there was a statistical difference (p = 0.001).
Conclusion:
Hypertensive elderly patients present decreased heart rate variability and decreased parasympathetic modulation when compared to normotensive elderly.
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