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Published on: April 7, 2023
Management of severe hypertension in the newborn
Janis M Dionne1, Joseph T Flynn2
1Department of Pediatrics, Division of Nephrology, University of British Columbia, BC Children's Hospital, Vancouver, Canada.
Insights
Severe hypertension in newborns is a medical emergency requiring prompt identification and management. Understanding its causes and utilizing intravenous medications are crucial for controlled blood pressure reduction and preventing complications.
Area of Science:
- Neonatal Medicine
- Pediatric Cardiology
- Critical Care
Background:
- Blood pressure is a critical vital sign, with abnormal levels posing significant morbidity and mortality risks.
- Normal blood pressure in neonates, particularly premature infants, changes rapidly, complicating the identification of hypertension.
- Severe neonatal hypertension is a medical emergency, often presenting with heart failure and other life-threatening conditions.
Purpose of the Study:
- To outline the identification, etiological factors, and management strategies for severe hypertension in newborns.
- To provide a focused review on recognizing and treating critical hypertensive crises in the neonatal population.
Main Methods:
- Review of existing literature on neonatal hypertension.
- Analysis of etiological factors and risk factors associated with severe hypertension in neonates.
- Discussion of current management approaches, including pharmacological interventions.
Main Results:
- Severe hypertension in neonates is a recognized emergency with identifiable causes.
- A range of antihypertensive medication classes have been utilized in neonates.
- Intravenous short-acting medications are the preferred method for controlled blood pressure reduction in severe cases.
Conclusions:
- Prompt identification and management of severe neonatal hypertension are essential.
- Understanding the underlying causes guides effective treatment strategies.
- Intravenous medications are critical for the safe and controlled management of hypertensive emergencies in newborns.
Abstract:
Blood pressure is considered a vital sign, as values too low or too high can be related with serious morbidity and mortality. In neonates, normal blood pressure values undergo rapid changes, especially in premature infants, making the recognition of abnormal blood pressures more challenging. Severe hypertension can occur in neonates and infants and is a medical emergency, often manifesting with congestive heart failure or other life-threatening complications. The cause or risk factors for the hypertension can usually be identified and may guide management. Most classes of antihypertensive medications have been used in the neonatal population. For severe hypertension, intravenous short-acting medications are preferred for a controlled reduction of blood pressure. In this article, we focus on identification, aetiology and management of severe hypertension in the newborn.
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