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Updated: Feb 26, 2026

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
Published on: September 12, 2016
LoCa LoPa myelopathy: is prevention better than cure?
Kamal Kishore Pandita1, Sushil Razdan2, Sarla Pandita3
1Visiting Consultant, Shri Mata Vaishno Devi Narayana Superspeciality Hospital, Kakryal, J&K, India.
Abstract:
Manifestations of primary hypoparathyroidism are produced by neuromuscular irritability or by extraosseous calcifications. We present a patient of primary hypoparathyroidism who had extensive calcification of brain parenchyma, and was suffering from chronic, generalised and progressive stiffness of body due to cervical compressive myelopathy, caused by calcification of posterior longitudinal ligament and ligamentum flavum. By presenting this case we wanted to emphasize the usefulness of meticulous clinical examination to differentiate the stiffness caused by myelopathy from that which is caused by possible coexisting extrapyramidal disorder. This case presentation also builds the hypothesis that early diagnosis and institution of early and appropriate treatment has potential to prevent the complications arising from extraosseous calcifications in patients with primary hypoparathyroidism.
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