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Related Concept Videos

Heart Failure I: Introduction01:27

Heart Failure I: Introduction

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Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
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Functions of Thyroid Hormones01:18

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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
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Factors Influencing Heart Rate01:30

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The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
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Cardiac Output I:Effect of Heart Rate on Cardiac Output01:19

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Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
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Decreased pulse rate01:14

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Bradycardia is a medical condition in which the heart rate is slower than normal. It occurs when the heart's natural pacemaker, the sinus node, generates slower electrical impulses than the standard rhythm. In adults, bradycardia is diagnosed when the pulse rate falls below 60 beats per minute, indicating a deviation from the normal heart rate range.
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Imbalances in Cardiac Output01:26

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The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
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In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
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Hypothyroidism and the Heart.

Maja Udovcic1, Raul Herrera Pena1, Bhargavi Patham1

  • 1Houston Methodist Hospital, Houston, Texas.

Methodist Debakey Cardiovascular Journal
|July 26, 2017
PubMed
Summary
This summary is machine-generated.

Hypothyroidism significantly impacts heart function, affecting contractility, blood pressure, and rhythm. Treatment of hypothyroidism can positively alter these cardiovascular parameters.

Keywords:
hypothyroidismsubclinical hypothyroidismthyroid-stimulating hormonethyroxine

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Area of Science:

  • Cardiology
  • Endocrinology
  • Internal Medicine

Background:

  • Hypothyroidism is a prevalent endocrine disorder with significant cardiovascular implications.
  • Cardiac function is notably affected by thyroid hormone levels, influencing multiple hemodynamic parameters.

Purpose of the Study:

  • To review the cardiac effects of overt and subclinical hypothyroidism.
  • To summarize the impact of hypothyroidism treatment on cardiovascular parameters.

Main Methods:

  • Literature review of studies investigating hypothyroidism and cardiovascular function.
  • Analysis of clinical data on cardiac changes associated with thyroid dysfunction.

Main Results:

  • Hypothyroidism adversely affects cardiac contractility, increases vascular resistance, and can lead to arrhythmias.
  • Subclinical hypothyroidism also demonstrates detrimental cardiovascular effects, albeit often less pronounced.

Conclusions:

  • Thyroid hormone status is critical for maintaining normal cardiac function.
  • Effective management of hypothyroidism is essential for mitigating cardiovascular risks.