Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

5.2K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
5.2K
Biological Effects of Radiation02:59

Biological Effects of Radiation

18.3K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
18.3K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

9.0K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
9.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of Radiomics Parameters and Clinical Integration on Prognostication in Head and Neck Squamous Cell Carcinoma: A Multicenter Study.

Life (Basel, Switzerland)·2026
Same author

A Nomogram Predicts the Need for Internal Iliac Vein Dissection During Renal Transplantation: A Multicenter Collaborative Study.

Transplantation proceedings·2026
Same author

Upsetting experiences in the lives of neurodivergent young people: A qualitative analysis of accounts of adolescents diagnosed with attention-deficit/hyperactivity disorder and/or autism.

JCPP advances·2026
Same author

Proton Therapy for Head and Neck Adenoid Cystic Carcinoma: A Multi-institutional Review.

International journal of particle therapy·2026
Same author

Enable preclinical, high-precision image-guided radiotherapy research with a stand-alone small animal IGRT system.

Medical physics·2026
Same author

MiR-513a promotes human erythroid differentiation by modulating c-Jun.

FEBS open bio·2026

Related Experiment Video

Updated: Feb 26, 2026

Intracavernosal Pressure Recording to Evaluate Erectile Function in Rodents
08:03

Intracavernosal Pressure Recording to Evaluate Erectile Function in Rodents

Published on: June 6, 2018

15.2K

Radiation-induced erectile dysfunction: Recent advances and future directions.

Javed Mahmood1, Aksinija A Shamah1, T Michael Creed1

  • 1Division of Translational Radiation Sciences, Department of Radiation Oncology, School of Medicine, University of Maryland, Baltimore, Maryland.

Advances in Radiation Oncology
|July 26, 2017
PubMed
Summary

Radiation therapy for prostate cancer often causes erectile dysfunction (RiED). Research explores RiED mechanisms and novel treatments like stem cells and shockwave therapy to improve patient quality of life.

More Related Videos

Intracavernous Pressure Recording in a Cavernous Nerve Injury Rat Model
05:48

Intracavernous Pressure Recording in a Cavernous Nerve Injury Rat Model

Published on: September 20, 2021

2.0K
Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
09:49

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy

Published on: December 28, 2021

4.0K

Related Experiment Videos

Last Updated: Feb 26, 2026

Intracavernosal Pressure Recording to Evaluate Erectile Function in Rodents
08:03

Intracavernosal Pressure Recording to Evaluate Erectile Function in Rodents

Published on: June 6, 2018

15.2K
Intracavernous Pressure Recording in a Cavernous Nerve Injury Rat Model
05:48

Intracavernous Pressure Recording in a Cavernous Nerve Injury Rat Model

Published on: September 20, 2021

2.0K
Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
09:49

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy

Published on: December 28, 2021

4.0K

Area of Science:

  • Oncology
  • Urology
  • Radiology

Background:

  • Prostate cancer is a leading cause of cancer death in men.
  • Radiation therapy (RT) is a common treatment, but causes radiation-induced erectile dysfunction (RiED) in ~50% of patients within 5 years.
  • RiED significantly impacts patients' quality of life.

Purpose of the Study:

  • To review recent advances in understanding the mechanisms of RiED.
  • To summarize novel treatment modalities for mitigating or curing RiED.
  • To discuss potential molecular mechanisms and therapeutic strategies for RiED.

Main Methods:

  • Review of current research on RiED mechanisms, including arterial damage and nerve dysfunction.
  • Exploration of radiogenomic advances for biomarker identification.
  • Summary of emerging and established treatment options for RiED.

Main Results:

  • Prostate RT causes arterial damage and cavernous nerve dysfunction, contributing to RiED.
  • Radiogenomics aids in identifying biomarkers for radiation-induced toxicity.
  • Proton beam therapy offers targeted treatment with reduced off-target damage.

Conclusions:

  • Understanding RiED mechanisms is crucial for developing effective treatments.
  • Novel strategies like stem cell therapy, shockwave therapy, and tissue engineering show promise for RiED.
  • Genomic and proteomic biomarkers can improve monitoring and management of radiation-induced damage.