Related Experiment Video
Updated: Aug 10, 2026
Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape
Published on: January 8, 2014
Orthogonal thiol-ene 'click' reactions: a powerful combination for fabrication and functionalization of patterned
N Cengiz1, T N Gevrek, R Sanyal
1Department of Chemistry, Bogazici University, 34342 Bebek, Istanbul, Turkey. amitav.sanyal@boun.edu.tr.
Abstract:
A combination of 'orthogonal' thiol-ene 'click' reactions is utilized for fabrication and functionalization of micro-patterned hydrogels. A furan-protected maleimide-containing parent copolymer is partially activated via the retro Diels-Alder reaction to obtain an 'orthogonally' functionalizable copolymer, where the different functional groups can be exploited for multi-functionalization or fabrication of functional hydrogels using combination of the nucleophilic and radical thiol-ene reactions.
