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Updated: Feb 26, 2026

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma

Published on: September 15, 2023

Radioactive Iodine Ablation Decrease Recurrences in Papillary Thyroid Microcarcinoma with Lateral Lymph Node

Shuai Xue¹, Peisong Wang¹, Jia Liu¹

¹Department of Thyroid Surgery, The 1st Hospital of Jilin University, Changchun, 130021, People's Republic of China.

World Journal of Surgery

|July 26, 2017

Summary

This summary is machine-generated.

Radioactive iodine (RAI) ablation may reduce recurrence in papillary thyroid microcarcinoma (PTMC) patients with lateral lymph node metastasis (LLNM). RAI treatment improved disease-free survival, particularly when lymph node ratios were high.

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Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

Area of Science:

Oncology
Endocrinology
Nuclear Medicine

Background:

Papillary thyroid microcarcinoma (PTMC) is a common thyroid cancer.
Lateral lymph node metastasis (LLNM) is a known risk factor for recurrence.
The role of radioactive iodine (RAI) ablation in managing PTMC with LLNM requires further clarification.

Purpose of the Study:

To investigate the impact of RAI ablation on recurrence risk in PTMC patients with LLNM.
To assess the effect of RAI on disease-free survival in this patient cohort.

Main Methods:

Retrospective study of 137 PTMC patients with LLNM who underwent surgery.
Analysis of disease-free survival based on RAI treatment status (RAI+ vs. RAI-).
Multivariate analysis using Cox's proportional hazards model to identify risk factors.

Main Results:

RAI (+) patients had significantly better disease-free survival than RAI (-) patients (p=0.0074).
5- and 10-year disease-free survival rates were higher in the RAI (+) group (100% and 96.81%) compared to the RAI (-) group (93.02% and 87.5%).
CLNM ratio and LLNM ratio were significant predictors of recurrence in the RAI (-) group.

Conclusions:

RAI ablation appears beneficial for PTMC patients with LLNM.
RAI may be particularly advantageous when the CLNM ratio or LLNM ratio exceeds 0.5.