Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

398
Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
398
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

462
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
462

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dissipative soliton generation and real-time dynamics in microresonator-filtered fiber lasers.

Light, science & applications·2022
Same author

Gastric cancer-derived exosomal miR-519a-3p promotes liver metastasis by inducing intrahepatic M2-like macrophage-mediated angiogenesis.

Journal of experimental & clinical cancer research : CR·2022
Same author

Effects of different modes of exercise on skeletal muscle mass and function and IGF-1 signaling during early aging in mice.

The Journal of experimental biology·2022
Same author

Optimal Control of False Information Clarification System under Major Emergencies Based on Differential Game Theory.

Computational intelligence and neuroscience·2022
Same author

Ionothermal Synthesis of Fully Conjugated Covalent Organic Frameworks for High-Capacity and Ultrastable Potassium-Ion Batteries.

Advanced materials (Deerfield Beach, Fla.)·2022
Same author

Circ-OMAC drives metastasis in oral squamous cell carcinoma.

Oral diseases·2022

Related Experiment Video

Updated: Feb 26, 2026

A Recovery Cardiopulmonary Bypass Model Without Transfusion or Inotropic Agents in Rats
09:54

A Recovery Cardiopulmonary Bypass Model Without Transfusion or Inotropic Agents in Rats

Published on: March 23, 2018

8.4K

Cardiopulmonary bypass time: every minute counts.

Sudharsan Madhavan1, Siew-Pang Chan2,3,4, Wei-Chuan Tan1

  • 1Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore.

The Journal of Cardiovascular Surgery
|July 26, 2017
PubMed
Summary

Prolonged cardiopulmonary bypass (CPB) times significantly predict mortality after coronary artery bypass grafting (CABG). Keeping CPB/graft time under 56 minutes and cumulative CPB time under 180 minutes is recommended to reduce adverse outcomes.

More Related Videos

Cardiopulmonary Bypass in a Mouse Model: A Novel Approach
08:08

Cardiopulmonary Bypass in a Mouse Model: A Novel Approach

Published on: September 22, 2017

11.7K
Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model
04:55

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model

Published on: May 26, 2023

1.4K

Related Experiment Videos

Last Updated: Feb 26, 2026

A Recovery Cardiopulmonary Bypass Model Without Transfusion or Inotropic Agents in Rats
09:54

A Recovery Cardiopulmonary Bypass Model Without Transfusion or Inotropic Agents in Rats

Published on: March 23, 2018

8.4K
Cardiopulmonary Bypass in a Mouse Model: A Novel Approach
08:08

Cardiopulmonary Bypass in a Mouse Model: A Novel Approach

Published on: September 22, 2017

11.7K
Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model
04:55

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model

Published on: May 26, 2023

1.4K

Area of Science:

  • Cardiovascular Surgery
  • Anesthesiology
  • Critical Care Medicine

Background:

  • Investigating the impact of cardiopulmonary bypass (CPB) duration on patient outcomes after cardiac surgery.
  • Identifying optimal thresholds for CPB per graft and cumulative CPB times.
  • Assessing the predictive accuracy of CPB times for mortality, alongside EuroSCORE II.

Purpose of the Study:

  • To determine the optimal cut-off values for cardiopulmonary bypass (CPB) per graft and cumulative CPB times.
  • To evaluate the predictive accuracy of these CPB time thresholds for postoperative mortality.
  • To analyze the association between CPB times and other adverse clinical events.

Main Methods:

  • Analysis of de-identified data from 1960 patients undergoing isolated on-pump coronary artery bypass grafting (CABG) between 2009 and 2014.
  • Utilizing a decision tree to establish risk strata for CPB per graft and cumulative CPB times.
  • Incorporating these risk strata into an augmented model for predicting clinical events.

Main Results:

  • Prolonged cumulative CPB time (>180 minutes) significantly predicted mortality, independent of EuroSCORE II.
  • Prolonged CPB per graft time (>56 minutes) showed a marginal, non-significant direct effect on mortality.
  • Indirect effects of prolonged CPB per graft time on mortality were observed through increased risks of complications, prolonged ICU stay (>48 hours), and mechanical ventilation (>24 hours).

Conclusions:

  • Extended cardiopulmonary bypass (CPB) times are predictive of adverse postoperative outcomes, particularly mortality.
  • Recommendations include maintaining CPB per graft time below 56 minutes and cumulative CPB time below 180 minutes.
  • Adhering to these CPB time guidelines may help minimize unfavorable clinical events following CABG surgery.