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Probing Tumour Proteostasis and the UPR with Serum Markers
Antoine Galmiche1, Chloé Sauzay1, Aline Houessinon1
1Service de Biochimie, Centre de Biologie Humaine (CBH), CHU Amiens Sud, France; EA4666, Université de Picardie Jules Verne (UPJV), Amiens, France.
Trends in Cancer
|July 26, 2017
Abstract:
Tumour proteostasis and the unfolded protein response (UPR) are emerging drivers of tumour progression and important determinants of clinical efficacy of cancer therapy. Recent findings indicate that they also regulate the production of protein tumour markers. Here, we discuss how this new knowledge opens up new perspectives for cancer therapeutics.
