Hemostasis pad combined with compression device after transradial coronary procedures: A randomized controlled trial

Area of Science:

• Cardiology
• Vascular Surgery
• Biomaterials

Background:

• Arterial access and achieving hemostasis are critical steps in percutaneous coronary procedures.
• Transradial access is a common approach for coronary angiography and interventions.

Purpose of the Study:

• To evaluate the efficacy of chitosan-based pads combined with compression devices for hemostasis after transradial coronary procedures.
• To compare the time to hemostasis using chitosan pads versus compression devices alone.

Main Methods:

• A single-center, open-label, randomized controlled trial was conducted.
• Patients undergoing transradial coronary angiography/intervention were randomized (2:1) to receive either a compression device with a chitosan-based pad (study group) or compression devices alone (control group).
• The primary endpoint was the time to achieve hemostasis.

Main Results:

• Ninety-five patients were enrolled, with 59 in the study group and 36 in the control group.
• The time to hemostasis was significantly shorter in the study group compared to the control group (p<0.001).
• Both groups demonstrated low rates of vascular complications.

Conclusions:

• The use of a chitosan-based hemostasis pad with rotatory compression devices is a safe and effective method for achieving hemostasis after radial artery access.
• This combination strategy offers an improved approach to managing hemostasis following transradial interventions.