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Vitamin D Deficiency, Supplementation, and Cardiovascular Health
Naveen Trehan1, Luis Afonso, Diane L Levine
1From the *Department of Internal Medicine, Detroit Medical Center/Wayne State University School of Medicine, Detroit, MI; †Division of Cardiology, Detroit Medical Center/Wayne State University School of Medicine, Detroit, MI; and ‡Department of Emergency Medicine and Cardiovascular Research Institute, Integrated Biosciences Center, Wayne State University School of Medicine, Detroit, MI.
Abstract:
Vitamin D has been traditionally recognized as a vitamin quintessential for bone-mineral health. In the past 2 decades, numerous experimental and observational studies have highlighted the role of vitamin D in immunity, metabolic syndrome (obesity and diabetes), cancers, renal disease, memory, and neurological dysfunction. In this article, we review important studies that focused on the impact of vitamin D on blood pressure, myocardial infarction, peripheral arterial disease, heart failure, and statin intolerance. Amidst the current pool of ambiguous evidence, we intend to discuss the role of vitamin D in "high-value cardiovascular health care".
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