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Updated: Feb 25, 2026

Identification of Post-translational Modifications of Plant Protein Complexes
Published on: February 22, 2014
Emerging Insights into the Functions of Pathogenesis-Related Protein 1
Susan Breen1, Simon J Williams1, Megan Outram2
1Plant Sciences Division, Research School of Biology, The Australian National University, Canberra 2601, Australia.
Abstract:
The members of the pathogenesis-related protein 1 (PR-1) family are among the most abundantly produced proteins in plants on pathogen attack, and PR-1 gene expression has long been used as a marker for salicylic acid-mediated disease resistance. However, despite considerable interest over several decades, their requirement and role in plant defence remains poorly understood. Recent reports have emerged demonstrating that PR-1 proteins possess sterol-binding activity, harbour an embedded defence signalling peptide, and are targeted by plant pathogens during host infection. These studies have re-energised the field and provided long-awaited insights into a possible PR-1 function. Here we review the current status of PR-1 proteins and discuss how these recent advances shed light on putative roles for these enigmatic proteins.
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