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Asymptomatic choroidal tubercle in a patient with Crohn's disease on adalimumab treatment
V M Asensio-Sánchez1, L Díaz-Cabanas1, A Martín-Prieto1
1Servicio de Oftalmología, Hospital Clínico Universitario, Valladolid, España.
Introduction:
Adalimumab, an anti-tumour necrosis factor alpha therapy for active Crohn's disease (CD), is associated with increased risks of tuberculosis infection.
Case Report:
The case is presented of a 48 year-old male with active CD on treatment with adalimumab. After three months, he developed a miliary pulmonary tuberculosis infection, with a solitary non-reactive choroidal tubercle temporal-superior to the optic disc being found in an ophthalmological study. Fluorescein angiography showed late hyperfluorescence in a staining pattern. Optic coherence tomography showed a flat mass without serous retinal detachment. The choroidal tubercle slowly regressed with antituberculosis therapy.
Discussion:
Choroidal tubercles with no vitreo-retinal symptomatology can be present in patients with CD and on treatment with adalimumab.
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