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Published on: July 18, 2014
Adult congenital heart disease in Greece: Preliminary data from the CHALLENGE registry
G Giannakoulas1, K Vasiliadis2, A Frogoudaki3
1Department of Cardiology, AHEPA University Hospital, Thessaloniki, Greece.
Insights
Adults with congenital heart disease (ACHD) in Greece are a growing population. The CHALLENGE registry identified their characteristics, highlighting the need for specialized care and resource allocation for these complex patients.
Area of Science:
- Cardiology
- Public Health
Background:
- Increasing survival rates for congenital heart disease (CHD) lead to a growing adult population (ACHD) facing long-term complications.
- Understanding the specific demographic and clinical profiles of ACHD patients is crucial for effective management.
Purpose of the Study:
- To investigate the demographic and clinical characteristics of adult patients with congenital heart disease (ACHD) in Greece.
- To establish baseline data for the CHALLENGE registry, aiding future research and resource allocation.
Main Methods:
- The CHALLENGE (Adult Congenital Heart Disease Registry) was initiated in January 2012.
- 16 specialized centers nationwide enrolled patients with structural CHD over 16 years old.
- Data from 2115 registered ACHD patients were analyzed.
Main Results:
- The ACHD population (mean age 38) comprised 52% women, with 47% mild, 37% moderate, and 15% severe disease.
- Atrial septal defect (ASD) was the most common diagnosis (33%); 92% were asymptomatic or mildly symptomatic.
- 12% were elderly (>60), half had prior open-heart surgery, and 39% were on cardiac medications.
Conclusions:
- Adult congenital heart disease (ACHD) represents an emerging patient group requiring dedicated attention.
- National prospective registries like CHALLENGE are vital for identifying patient needs and optimizing resource allocation.
- This registry provides essential data for understanding and managing the complexities of ACHD in Greece.
Background:
The majority of patients with congenital heart disease (CHD), nowadays, survives into adulthood and is faced with long-term complications. We aimed to study the basic demographic and clinical characteristics of adult patients with congenital heart disease (ACHD) in Greece.
Methods:
A registry named CHALLENGE (Adult Congenital Heart Disease Registry. A registry from Hellenic Cardiology Society) was initiated in January 2012. Patients with structural CHD older than 16years old were enrolled by 16 specialized centers nationwide.
Results:
Out of a population of 2115 patients with ACHD, who have been registered, (mean age 38years (SD 16), 52% women), 47% were classified as suffering from mild, 37% from moderate and 15% from severe ACHD. Atrial septal defect (ASD) was the most prevalent diagnosis (33%). The vast majority of ACHD patients (92%) was asymptomatic or mildly symptomatic (NYHA class I/II). The most symptomatic patients were suffering from an ASD, most often the elderly or those under targeted therapy for pulmonary arterial hypertension. Elderly patients (>60years old) accounted for 12% of the ACHD population. Half of patients had undergone at least one open-heart surgery, while 39% were under cardiac medications (15% under antiarrhythmic drugs, 16% under anticoagulants, 16% under medications for heart failure and 4% under targeted therapy for pulmonary arterial hypertension).
Conclusions:
ACHD patients are an emerging patient population and national prospective registries such as CHALLENGE are of unique importance in order to identify the ongoing needs of these patients and match them with the appropriate resource allocation.
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