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Diffuse dermal angiomatosis mimicking inflammatory breast carcinoma
Yiang Hui1, Christopher P Elco1, Nicole F Heinl1
1Department of Pathology, Alpert Medical School of Brown University, Providence, RI, USA.
The Breast Journal
|July 27, 2017
Summary
Diffuse dermal angiomatosis (DDA) is a rare breast skin condition. This case highlights DDA
Area of Science:
- Dermatology
- Pathology
- Oncology
Background:
- Diffuse dermal angiomatosis (DDA) is a rare reactive angioendotheliomatosis subtype.
- Biopsy-proven DDA cases of the breast skin are infrequently reported in medical literature.
Observation:
- A 49-year-old female presented with a tender, indurated, erythematous, weeping, puckered lesion with ulceration on the breast.
- Mammography revealed diffuse cutaneous and trabecular thickening, raising concern for inflammatory breast carcinoma.
Findings:
- Punch biopsy confirmed findings consistent with diffuse dermal angiomatosis.
- This case represents the first reported instance of DDA clinically and radiologically mimicking inflammatory breast carcinoma.
Implications:
- DDA can present with clinical and radiologic features that closely resemble inflammatory breast carcinoma.
- Increased awareness of DDA is crucial for accurate diagnosis and appropriate patient management, avoiding misdiagnosis of malignancy.
- This case underscores the importance of histopathological examination for definitive diagnosis in breast lesions with ambiguous presentations.
