Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies for Cardiovascular System III: X-Ray01:20

Imaging Studies for Cardiovascular System III: X-Ray

526
The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
526
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

412
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
412

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tension TRAAKer: a chemigenetic fluorescent membrane tension reporter.

bioRxiv : the preprint server for biology·2026
Same author

A chemical-genetic approach to target voltage-sensitive fluorophores to mitochondria.

Mitochondrial communications·2026
Same author

Membrane potential and feedback dynamics regulate CatSper-mediated progesterone signaling in human sperm.

bioRxiv : the preprint server for biology·2025
Same author

Controlling Electron Flow in Carbofluorescein Voltage Indicators.

ACS chemical biology·2025
Same author

Bis(trifluoromethyl)carborhodamines: Highly Fluorogenic, Far-Red to Near-Infrared Dyes for Live Cell Fluorescence Microscopy, Activity-Based Sensing, and Single-Molecule Microscopy.

Journal of the American Chemical Society·2025
Same author

Ratio-based indicators for cytosolic Ca<sup>2+</sup> with visible light excitation.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same journal

Aromatic Cage-Directed Azide-Methyllysine Photochemistry for Profiling Nonhistone Interacting Partners of the MeCP2 Methyl-CpG-Binding Domain.

Biochemistry·2026
Same journal

Differential Hydroxypyruvate Processing by <i>E. coli</i> and <i>P. aeruginosa</i> DXP Synthases Reveals Preferential Xylulose 5-Phosphate Formation by the <i>P. aeruginosa</i> Enzyme.

Biochemistry·2026
Same journal

Structural and Functional Characterization of Heterologous Nitrogenase Complexes.

Biochemistry·2026
Same journal

Discovery of Bacterial Unspecific Peroxygenases.

Biochemistry·2026
Same journal

Lactate Biology: Subcellular Routing and Chemical Form Define Function.

Biochemistry·2026
Same journal

Nature's Anaerobic Toolkit: Glycyl Radical Enzymes and Their Expanding Functional and Mechanistic Diversity.

Biochemistry·2026
See all related articles

Related Experiment Video

Updated: Feb 25, 2026

Imaging Membrane Potential with Two Types of Genetically Encoded Fluorescent Voltage Sensors
09:57

Imaging Membrane Potential with Two Types of Genetically Encoded Fluorescent Voltage Sensors

Published on: February 4, 2016

11.3K

Voltage Imaging: Pitfalls and Potential.

Rishikesh U Kulkarni1, Evan W Miller1

  • 1Department of Chemistry, ‡Department of Molecular and Cell Biology, and §Helen Wills Neuroscience Institute, University of California , Berkeley, California 94720, United States.

Biochemistry
|July 27, 2017
PubMed
Summary
This summary is machine-generated.

New optical tools, including small-molecule and genetically encoded indicators, are revolutionizing how scientists study neural circuits. These voltage imaging strategies offer unprecedented insights into neuronal activity for understanding behavior and sensation.

More Related Videos

Optical Imaging of Isolated Murine Ventricular Myocytes
11:32

Optical Imaging of Isolated Murine Ventricular Myocytes

Published on: January 17, 2020

6.7K
Voltage-sensitive Dye Recording from Axons, Dendrites and Dendritic Spines of Individual Neurons in Brain Slices
12:51

Voltage-sensitive Dye Recording from Axons, Dendrites and Dendritic Spines of Individual Neurons in Brain Slices

Published on: November 29, 2012

17.3K

Related Experiment Videos

Last Updated: Feb 25, 2026

Imaging Membrane Potential with Two Types of Genetically Encoded Fluorescent Voltage Sensors
09:57

Imaging Membrane Potential with Two Types of Genetically Encoded Fluorescent Voltage Sensors

Published on: February 4, 2016

11.3K
Optical Imaging of Isolated Murine Ventricular Myocytes
11:32

Optical Imaging of Isolated Murine Ventricular Myocytes

Published on: January 17, 2020

6.7K
Voltage-sensitive Dye Recording from Axons, Dendrites and Dendritic Spines of Individual Neurons in Brain Slices
12:51

Voltage-sensitive Dye Recording from Axons, Dendrites and Dendritic Spines of Individual Neurons in Brain Slices

Published on: November 29, 2012

17.3K

Area of Science:

  • Neuroscience
  • Biophysics
  • Optical Imaging

Background:

  • Dissecting neural circuit activity is crucial for understanding behavior and sensation.
  • Optical methods offer a promising avenue for interrogating neuronal membrane potential changes.
  • Recent years have seen rapid advancements in voltage imaging technologies.

Purpose of the Study:

  • To provide a comprehensive overview of recent developments in optical voltage imaging.
  • To discuss both small-molecule and genetically encoded fluorescent indicators.
  • To compare the unique challenges of voltage imaging with calcium (Ca2+) imaging.

Main Methods:

  • Survey of recent advances in small-molecule fluorescent indicators utilizing photoinduced electron transfer.
  • Review of refinements in voltage-sensitive fluorescent proteins.
  • Exploration of novel opsin-based strategies for voltage monitoring.

Main Results:

  • Emergence of diverse voltage imaging strategies, including small-molecule, genetically encoded, and opsin-based approaches.
  • Significant progress in indicator sensitivity and specificity for membrane potential changes.
  • Identification of key challenges distinguishing voltage imaging from calcium imaging.

Conclusions:

  • Optical voltage imaging is rapidly advancing, offering powerful tools for neuroscience research.
  • Continued development of fluorescent indicators promises to deepen our understanding of neural circuits.
  • Addressing the specific challenges of voltage imaging will further enhance its utility in neuroscience.