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Myopathy in hyperthyroidism as a consequence of rapid reduction of thyroid hormone: A case report
Qianrui Li1, Yuping Liu, Qianying Zhang
1Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China.
Rationale:
Myalgia and elevated creatine kinase (CK) are occasionally observed during the treatment of hyperthyroid patients. Relative hypothyroidism resulted from rapid thyroid hormone reduction had been promoted as a plausible cause of these myopathic changes, however rarely reported.
Patient Concerns:
We hereby presented a 20-year-old female with Grave's disease, who developed myopathy and elevated CK during rapid correction of thyroid hormone.
Diagnoses:
Relative hypothyroidism-induced myopathy.
Interventions:
Antithyroid drug (ATD) dosage was reduced without levothyroxine replacement.
Outcomes:
The muscular symptoms were recovered with CK level returned to normal after adoption of the euthyroid status.
Lessons:
Differentiation of relative hypothyroidism from other causes of myopathy, especially with the effect of ATD, is important for clinical practice, although difficult in many cases.
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