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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

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Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
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Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Other Disorders of Digestive System01:30

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The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

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Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
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Related Experiment Video

Updated: Feb 25, 2026

Author Spotlight: Isolation and Characterization of Equine Submucosal Enteric Glia — Implications for Preventing Postoperative Complications in Colic Surgery
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Author Spotlight: Isolation and Characterization of Equine Submucosal Enteric Glia — Implications for Preventing Postoperative Complications in Colic Surgery

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Systemic Inflammatory Response Syndrome following Gastrointestinal Surgery.

U Koirala1, P B Thapa2, M R Joshi2

  • 1Department of Surgery, Kathmandu Model Hospital, Kathmandu, Nepal.

JNMA; Journal of the Nepal Medical Association
|July 27, 2017
PubMed
Summary

Systemic inflammatory response syndrome (SIRS) after surgery indicates complications. Prolonged SIRS correlates with increased morbidity and mortality, highlighting its clinical significance for patient outcomes.

Keywords:
gastrointestinal surgery; multiple organ dysfunction syndrome; systemic inflammatory response syndrome.

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Area of Science:

  • Surgical critical care
  • Inflammatory response
  • Postoperative complications

Background:

  • Systemic inflammatory response syndrome (SIRS) post-surgery is linked to adverse outcomes.
  • Early detection of SIRS is crucial for managing postoperative complications.

Purpose of the Study:

  • To determine the clinical significance of SIRS in postoperative patients.
  • To investigate the link between SIRS duration and patient morbidity/mortality.

Main Methods:

  • Retrospective analysis of 30 gastrointestinal surgery patients diagnosed with SIRS.
  • Evaluation of preoperative status, surgical stress, and postoperative SIRS, complications, and organ dysfunction.

Main Results:

  • SIRS duration correlated with surgical stress markers like blood loss and operation time.
  • Prolonged SIRS and septic complications were associated with multiple organ dysfunction syndrome and higher mortality.

Conclusions:

  • SIRS is a valuable indicator for identifying postoperative complications and organ dysfunction.
  • Prompt resolution of SIRS may prevent organ dysfunction progression and reduce mortality.