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Plasmodesmata

Plasmodesmata

The organs in a multicellular organism’s body are made up of tissues formed by cells. To work together cohesively, cells must communicate. One way that cells communicate is through direct contact with other cells. The points of contact that connect adjacent cells are called intercellular junctions.

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Updated: Feb 25, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Published on: March 30, 2018

Plasmablastic Lymphoma.

S Bhusal¹, B Acharya¹, S Chapagain¹

¹Department of Clinical Oncology, Bir Hospital, National Academy of Medical Sciences, Kathmandu, Nepal.

JNMA; Journal of the Nepal Medical Association

|July 27, 2017

Summary

This summary is machine-generated.

Plasmablastic lymphoma, a rare aggressive cancer, typically affects immunocompromised patients. This report details a unique case in an immunocompetent woman, highlighting atypical presentations of this challenging lymphoma.

Keywords:

plasmablastic lymphoma; urothelial carcinoma; SVCO.

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Last Updated: Feb 25, 2026

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Area of Science:

Hematology
Oncology
Pathology

Background:

Plasmablastic lymphoma (PBL) is an aggressive non-Hodgkin lymphoma.
PBL is strongly associated with human immunodeficiency virus (HIV) infection and other immunodeficiency states.
The aggressive nature and poor prognosis of PBL present significant clinical challenges, with no established standard of care.

Observation:

This report focuses on a unique case of PBL in a 67-year-old immunocompetent female.
The patient presented without the typical clinical features commonly associated with PBL.
A relevant medical history included urothelial carcinoma diagnosed three months prior to the current presentation.

Findings:

The case highlights the diagnostic challenges posed by atypical presentations of plasmablastic lymphoma.
Immunocompetence does not exclude the possibility of developing this rare lymphoma.
The patient's prior history of urothelial carcinoma may be a relevant factor in her presentation.

Implications:

This case underscores the need for a high index of suspicion for plasmablastic lymphoma, even in immunocompetent individuals presenting atypically.
Further research is warranted to understand the potential role of prior malignancies or other factors in the development of PBL in immunocompetent hosts.
The report contributes to the limited literature on non-conventional presentations of plasmablastic lymphoma, aiding clinicians in diagnosis and management strategies.