Related Experiment Video

Updated: Feb 25, 2026

Stereotactically-guided Ablation of the Rat Auditory Cortex, and Localization of the Lesion in the Brain
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Stereotactically-guided Ablation of the Rat Auditory Cortex, and Localization of the Lesion in the Brain

Published on: October 11, 2017

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Cortical Interneurons Differentially Regulate the Effects of Acoustic Context

Elizabeth A K Phillips1, Christoph E Schreiner1, Andrea R Hasenstaub1

  • 1Coleman Memorial Laboratory, University of California, San Francisco, San Francisco, CA 94158, USA; Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Otolaryngology - Head and Neck Surgery, University of California, San Francisco, San Francisco, CA 94158, USA; Kavli Institute for Theoretical Physics, University of California, Santa Barbara, Santa Barbara, CA 93106, USA.

Cell Reports
|July 27, 2017
PubMed
Summary

Specific interneurons in the auditory cortex control how sounds are perceived based on context. Suppressing somatostatin-positive (Sst+) interneurons weakens forward suppression, while inactivating parvalbumin-positive (Pvalb+) interneurons strengthens it.

Keywords:
auditory cortexforward suppressioninterneurons

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