Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Inflammatory Bowel Disease I: Ulcerative Colitis

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...

Bacterial Phylum Spirochaetes

Bacterial Phylum Spirochaetes

Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...

Acute Pyelonephritis II: Diagnostic Studies and Management

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...

Chronic Bowel Disorders: Introduction

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...

Endocarditis I: Introduction

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...

Inflammatory Bowel Disease II: Crohn's Disease

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Widening Colon Cancer Disparities Post-Pandemic in Disaggregated Asian American and Pacific Islander Populations (2004-2021).

Journal of immigrant and minority health·2026

Same author

Validation of Claims-Based Algorithms to Classify Thoracic Radiation Therapy Courses.

JCO clinical cancer informatics·2026

Same author

Stereotactic radiosurgery for brain metastases: evolving practice patterns from the national cancer database (2004-2020).

Journal of neuro-oncology·2025

Same author

Examining Barriers to Practice in Genitourinary and Gynecologic Radiation Oncology: Results from 2 Nationwide Surveys.

Advances in radiation oncology·2025

Same author

Meditation modalities for ADHD in minority pediatric populations in the USA: a scoping review.

Health promotion perspectives·2024

Same author

CSCO breast cancer management guidelines 2022: Australian perspective.

Translational breast cancer research : a journal focusing on translational research in breast cancer·2024

Search research articles

Related Experiment Video

Updated: Feb 25, 2026

Culturing and Maintaining Clostridium difficile in an Anaerobic Environment

Culturing and Maintaining Clostridium difficile in an Anaerobic Environment

Published on: September 14, 2013

Discitis and Clostridium perfringens bacteraemia.

Chen Han Yong^1,2, Miranda Lam^1,2

¹Division of Medical Sub-Specialties, Lyell McEwin Hospital, Elizabeth Vale, South Australia, Australia.

BMJ Case Reports

|July 28, 2017

Summary

This case report highlights a rare instance of infectious discitis caused by Clostridium perfringens bacteremia. Prompt antibiotic treatment led to a favorable outcome, emphasizing timely diagnosis and intervention for spinal infections.

Keywords:

infectious diseases

More Related Videos

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Published on: December 10, 2016

The Citrobacter rodentium Mouse Model: Studying Pathogen and Host Contributions to Infectious Colitis

The Citrobacter rodentium Mouse Model: Studying Pathogen and Host Contributions to Infectious Colitis

Published on: February 19, 2013

Related Experiment Videos

Last Updated: Feb 25, 2026

Culturing and Maintaining Clostridium difficile in an Anaerobic Environment

Culturing and Maintaining Clostridium difficile in an Anaerobic Environment

Published on: September 14, 2013

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Published on: December 10, 2016

The Citrobacter rodentium Mouse Model: Studying Pathogen and Host Contributions to Infectious Colitis

The Citrobacter rodentium Mouse Model: Studying Pathogen and Host Contributions to Infectious Colitis

Published on: February 19, 2013

Area of Science:

Infectious Diseases
Spinal Infections
Bacteremia

Background:

Discitis and osteomyelitis diagnosis can be challenging due to non-specific symptoms.
Clostridium perfringens bacteremia is a rare but serious condition.
Spinal infections require prompt and accurate diagnosis for effective management.

Observation:

An 80-year-old male presented with infectious T10/T11 discitis following Clostridium perfringens bacteraemia.
Despite extensive investigations, the specific causative agent for discitis remained unidentified.

Findings:

Intravenous piperacillin/tazobactam was administered, resulting in a positive clinical response.
The patient achieved a favorable clinical outcome following treatment.

Implications:

This case highlights the importance of considering Clostridium perfringens in spinal infections.
Timely empirical antimicrobial therapy, guided by patient stability, is essential for maximizing microbiological yield in suspected discitis/osteomyelitis.