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Functional Diversity of AAA+ Protease Complexes in Bacillus subtilis

Alexander K W Elsholz1, Marlene S Birk1, Emmanuelle Charpentier1,2,3

  • 1Department of Regulation in Infection Biology, Max Planck Institute for Infection BiologyBerlin, Germany.

Frontiers in Molecular Biosciences
|July 28, 2017
PubMed
Summary

AAA+ proteases regulate protein balance, stress responses, and development in Bacillus subtilis. Their adaptor proteins are key to these processes and potential antibiotic targets.

Keywords:
AAA+ protease complexesBacillus subtilisHsp100/Clp proteinsMcsBadaptor proteinschaperonesprotein quality controlregulatory proteolysis

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