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Screening of Axonal Degeneration in Carpal Tunnel Syndrome Using Ultrasonography and Nerve Conduction Studies
Published on: January 11, 2019
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Does Diabetes Mellitus Influence Carpal Tunnel Syndrome?
Yoo Hwan Kim1,2, Kyung Sook Yang3, Hanjun Kim1
1Department of Neurology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea.
Journal of Clinical Neurology (Seoul, Korea)
|July 28, 2017
Summary
Diabetes mellitus (DM) may affect nerve conduction studies (NCS) in carpal tunnel syndrome (CTS) patients, but ultrasonography (US) showed no significant link between DM and CTS. Further research is needed to clarify this association.
Area of Science:
- Neurology
- Diabetology
- Musculoskeletal Imaging
Background:
- The relationship between diabetes mellitus (DM) and carpal tunnel syndrome (CTS) is debated.
- Previous studies have yielded conflicting results regarding DM as a risk factor for CTS.
Purpose of the Study:
- To investigate the association between DM and CTS.
- To utilize both ultrasonography (US) and nerve conduction study (NCS) data for a comprehensive analysis.
Main Methods:
- A prospective cohort of 230 subjects with suspected CTS was analyzed.
- Participants were categorized into four groups based on the presence of CTS and DM.
- Nerve conduction studies (NCS) and ultrasonography (US) measurements of the median nerve (MN) were compared across groups.
Main Results:
- Nerve conduction studies showed differences in median nerve (MN) parameters between diabetic and non-diabetic groups, irrespective of CTS.
- Specifically, MN action potential amplitude in females was significantly associated with DM (p<0.001).
- Ultrasonography (US) cross-sectional area (CSA) measurements did not reveal significant differences among the groups.
Conclusions:
- Nerve conduction studies (NCS) suggest potential differences in median nerve (MN) function related to diabetes mellitus (DM), independent of carpal tunnel syndrome (CTS).
- Ultrasonography (US) did not establish a statistically significant link between DM and CTS, indicating its limitations in this context.
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