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Updated: Feb 25, 2026

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
Published on: March 25, 2022
EUS-guided gastroenterostomy: a multicenter study comparing the direct and balloon-assisted techniques.
Yen-I Chen1, Rastislav Kunda2, Andrew C Storm3
1Division of Gastroenterology and Hepatology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA; Division of Gastroenterology and Hepatology, McGill University Health Center, McGill University, Montreal, Quebec, Canada.
Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) effectively treats gastric outlet obstruction (GOO). The direct technique offers a shorter procedure time compared to the balloon-assisted method, suggesting it may be preferred.
Area of Science:
- Gastroenterology
- Endoscopic procedures
- Surgical innovation
Background:
- Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) is an emerging treatment for gastric outlet obstruction (GOO).
- Existing EUS-GE techniques include direct and balloon-assisted methods.
- The role of EUS-GE in GOO management requires further definition.
Purpose of the Study:
- To compare the technical success and clinical outcomes of direct versus balloon-assisted EUS-GE.
- To evaluate procedure time and adverse events for both EUS-GE techniques.
- To further establish the utility of EUS-GE in managing GOO.
Main Methods:
- A multicenter, retrospective study of patients undergoing EUS-GE for GOO from January 2014 to October 2016.
- Patients were divided into direct (n=52) and balloon-assisted (n=22) technique groups.
- Primary outcome: technical success. Secondary outcomes: clinical success, procedure time, adverse events.
Main Results:
- Technical success rates were high and similar for both techniques (direct: 94.2%, balloon-assisted: 90.9%).
- The direct technique demonstrated significantly shorter procedure times (35.7 min vs 89.9 min).
- Clinical success rates were comparable (direct: 92.3%, balloon-assisted: 90.9%), with low adverse event rates.
Conclusions:
- EUS-GE is a safe and effective endoscopic treatment for gastric outlet obstruction.
- The direct EUS-GE technique may be preferable due to its shorter procedural duration.
- Further prospective studies are warranted to validate these findings.
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