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Updated: Feb 25, 2026

Optical Clearing and Imaging of Immunolabeled Kidney Tissue
Published on: July 22, 2019
Label-free molecular imaging of the kidney
Boone M Prentice1, Richard M Caprioli2, Vincent Vuiblet3
1Department of Biochemistry, Vanderbilt University, Nashville, Tennessee, USA; Mass Spectrometry Research Center, Vanderbilt University, Nashville, Tennessee, USA.
Abstract:
In this review, we will highlight technologies that enable scientists to study the molecular characteristics of tissues and/or cells without the need for antibodies or other labeling techniques. Specifically, we will focus on matrix-assisted laser desorption/ionization imaging mass spectrometry, infrared spectroscopy, and Raman spectroscopy.
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