Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple endocrine neoplasia, type III.

H S Koppang, E Aksdal, E Engebjerg

    International Journal of Oral and Maxillofacial Surgery
    |August 1, 1986
    PubMed
    Summary

    Multiple oral neuromas in a teen prompted screening for Multiple Endocrine Neoplasia (MEN) type III syndrome, revealing thyroid medullary carcinoma. Early recognition by dental professionals is vital for life-saving diagnosis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Nerve growth factor receptor (p75 NTR) and pattern of invasion predict poor prognosis in oral squamous cell carcinoma.

    Histopathology·2008
    Same author

    [Crohn disease of the oral cavity, illustrated by some cases].

    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke·2002
    Same author

    DNA content as a prognostic marker in patients with oral leukoplakia.

    The New England journal of medicine·2001
    Same author

    Glandular odontogenic cyst (sialo-odontogenic cyst): report of two cases and literature review of 45 previously reported cases.

    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·1998
    Same author

    Is the carbohydrate sialosyl-Tn a marker for altered, non-malignant activity in squamous epithelium in the head and neck region?

    The Journal of pathology·1995
    Same author

    Relationship between age and deposit of peritubular dentine.

    Gerodontology·1994

    Area of Science:

    • Endocrinology
    • Oncology
    • Oral Medicine

    Background:

    • Multiple endocrine neoplasia (MEN) syndromes are rare genetic disorders associated with tumor development in endocrine glands.
    • MEN type III is characterized by medullary thyroid carcinoma, pheochromocytoma, and mucosal neuromas.
    • Oral manifestations can be the earliest signs of MEN syndromes, necessitating awareness among dental professionals.

    Observation:

    • A 14-year-old female presented with multiple oral plexiform neuromas.
    • Screening for MEN type III syndrome was initiated due to the presence of oral neuromas.
    • The patient was diagnosed with MEN type III, including medullary thyroid carcinoma.

    Findings:

    • Medullary thyroid carcinoma was confirmed in the patient with oral neuromas.
    • Surgical intervention involved a total thyroidectomy.
    • Extensive tumor infiltration precluded complete surgical removal of the thyroid carcinoma.

    Implications:

    • This case highlights the critical role of dental practitioners and oral surgeons in the early detection of MEN type III syndrome.
    • Prompt recognition of oral signs like neuromas can lead to timely diagnosis and potentially life-saving interventions.
    • Increased awareness of rare conditions like MEN type III among healthcare providers is essential for improved patient outcomes.

    Related Experiment Videos