Related Experiment Video
Updated: Feb 25, 2026

Leprdb Mouse Model of Type 2 Diabetes: Pancreatic Islet Isolation and Live-cell 2-Photon Imaging Of Intact Islets
Published on: May 11, 2015
Type 2 diabetes in a Senegalese rural area
Priscilla Duboz1, Gilles Boëtsch1, Lamine Gueye1
1Priscilla Duboz, UMI 3189 Environnement, Santé, Sociétés, CNRS/Université Cheikh Anta Diop/Université Gaston Berger/USTTB/CNRST, International Human-Environment Observatory Tessekere, Faculté de Médecine de Dakar, Université Cheikh Anta Diop, Dakar, Senegal.
Diabetes prevalence in rural Tessekere, Senegal, is high, with impaired fasting glucose affecting 6.6% and diabetes 4.2%. Elevated Body Mass Index (BMI) is a key risk factor, highlighting the need for early intervention in sub-Saharan Africa.
Area of Science:
- Public Health
- Epidemiology
- Diabetology
Background:
- Diabetes and impaired fasting glucose (IFG) are significant health challenges globally.
- Rural sub-Saharan Africa faces a growing burden of diabetes, necessitating local prevalence data.
Purpose of the Study:
- To determine the prevalence of diabetes and IFG in Tessekere, Senegal.
- To identify risk factors associated with diabetes in this rural population.
Main Methods:
- A 2015 survey of 500 adults (≥20 years) in Tessekere, Senegal.
- Data collection included sociodemographics, health variables, capillary blood glucose, and anthropometrics.
- Statistical analysis involved bivariate tests and binary logistic regression.
Main Results:
- Impaired fasting glucose (IFG) prevalence was 6.6%.
- Diabetes prevalence (FBG ≥ 126 mg/dL or treatment) was 4.2%.
- Higher Body Mass Index (BMI) was significantly associated with diabetes after adjusting for other factors.
Conclusions:
- Diabetes and IFG prevalence in Tessekere align with the higher range reported for rural sub-Saharan Africa.
- Diabetes represents a critical public health issue in rural settings.
- Identified risk factors suggest an early stage of the epidemic, amenable to intervention.
Related Concept Videos
Diabetes Mellitus: Type 2 and Gestational
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Diabetes: Symptoms, Diagnosis, and Complications
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...

