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Readmissions after continuous flow left ventricular assist device implantation.

Mitsutoshi Kimura1, Kan Nawata2,3, Osamu Kinoshita2

  • 1Department of Cardiac Surgery, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan. kimuram-sur@h.u-tokyo.ac.jp.

Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs
|July 29, 2017
PubMed
Summary

Readmission is common for continuous flow left ventricular assist device (CF-LVAD) patients, with driveline infection being the most frequent cause. Repeated readmissions are associated with poorer quality of life.

Keywords:
Continuous flowDriveline infectionLeft ventricular assist deviceReadmission

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Area of Science:

  • Cardiology
  • Medical Devices
  • Health Outcomes Research

Background:

  • Continuous flow left ventricular assist device (CF-LVAD) therapy significantly improves survival in advanced heart failure patients.
  • Despite therapeutic advancements, CF-LVAD recipients experience high hospital readmission rates, impacting long-term outcomes and healthcare resource utilization.

Purpose of the Study:

  • To retrospectively analyze the incidence, etiology, and patterns of hospital readmissions in CF-LVAD patients post-discharge.
  • To identify factors associated with readmission and their impact on patient quality of life.

Main Methods:

  • Retrospective analysis of 90 CF-LVAD patients discharged home between April 2011 and March 2016.
  • Data collection included readmission frequency, duration, etiology, and patient-reported quality of life using the EuroQol 5 dimensions questionnaire.

Main Results:

  • 81% of patients experienced 236 readmissions (214 unplanned) over a mean follow-up of 713 days.
  • The most common readmission cause was driveline infection (36%), followed by stroke (9%).
  • Patients with repeated unplanned readmissions had significantly lower quality of life scores.

Conclusions:

  • Hospital readmission is a frequent complication in CF-LVAD therapy, primarily driven by driveline infections.
  • Shorter intervals between readmissions were observed in patients with recurrent admissions, suggesting a need for targeted interventions.