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Assessment of left atrial function in patients with hypertrophic cardiomyopathy using two-dimensional strain: a

Jun Huang1, Zi-Ning Yan2, Yi-Fei Rui2

  • 1Department of Echocardiography, ChangZhou N. 2 People's Hospital Affiliated to NanJing Medical University, ChangZhou, China - 305669112@qq.com.

Minerva Cardioangiologica
|July 29, 2017
PubMed

Insights

Two-dimensional speckle tracking imaging (2D-STI) reveals impaired left atrial (LA) function in hypertrophic cardiomyopathy (HCM) patients. This method accurately assesses LA strain and strain rate, aiding in clinical management.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Biomedical Engineering

Background:

  • Hypertrophic cardiomyopathy (HCM) is a prevalent cardiac condition.
  • Left atrial (LA) function is crucial for diastolic function in HCM patients.
  • Two-dimensional speckle tracking imaging (2D-STI) is utilized to evaluate LA function.

Purpose of the Study:

  • To assess left atrial (LA) function in patients with hypertrophic cardiomyopathy (HCM) using 2D-STI.
  • To compare LA function parameters between HCM patients and healthy individuals.
  • To investigate the correlation between LA function and other cardiac parameters.

Main Methods:

  • Studied 34 HCM patients and 34 matched healthy controls.
  • Measured LA Volume-Derived Index using 2D ultrasonic images.
  • Assessed LA strain (reservoir, conduit, booster pump) and strain rate (SR).

Main Results:

  • Significant differences in LA reservoir, conduit, and booster pump functions were observed between HCM patients and controls, with reduced function in HCM.
  • LA reservoir function correlated with LA ejection fraction (LAEF), LA Expansion Index, and left ventricular (LV) global longitudinal strain.
  • LA conduit and booster pump functions showed correlations with specific echocardiographic parameters and LV global longitudinal strain.

Conclusions:

  • 2D-STI effectively identifies LA dysfunction in HCM by measuring LA strain and strain rate.
  • Accurate assessment of LA function using 2D-STI may offer clinical value in managing HCM patients.
  • This imaging technique provides a convenient method for evaluating subtle changes in cardiac function.
Abstract

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