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Origin and regulation of a lung repair kit
1Department of Pulmonary Medicine, the University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.
Nature Cell Biology
|July 29, 2017
Abstract:
The lung undergoes a striking repair process in response to severe injuries such as influenza infection. A study now demonstrates that associated stem/progenitor cells are heterogeneous in nature and comprise subpopulations dominated by hypoxia/Notch or Wnt signalling. Modulation of this heterogeneity in favour of functional repair may have therapeutic value.

