Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Attenuated Total Reflectance (ATR) Infrared Spectroscopy: Overview01:13

Attenuated Total Reflectance (ATR) Infrared Spectroscopy: Overview

1.4K
Attenuated total reflectance (ATR) infrared spectroscopy is a powerful analytical technique used to study the composition of materials. It is widely employed in chemistry, materials science, forensic science, and other fields where sample characterization is required. ATR has several advantages over traditional transmission IR spectroscopy, including the requirement of little to no sample preparation and the ability to analyze a wide range of samples.
The ATR process begins by directing a beam...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Photonic crystal band edge coupled enhanced fluorescence from magneto-plasmonic cryosoret nano-assemblies for ultra-sensitive detection.

APL materials·2026
Same author

Ultrasensitive non-enzymatic protein detection using proximity immunoassay with photonic resonator absorption microscopy.

Npj biosensing·2026
Same author

Selective capture and digital counting of intact HIV pseudovirus using designer DNA nets, tethered motion, and photonic resonator interferometric scattering microscopy.

APL bioengineering·2026
Same author

A 1.5D Photonic Crystal Interface for Prism-Free, Near-Normal, Low-Background Photoluminescence.

Nano letters·2026
Same author

A Gentle Push for a Giant Leap: Harnessing Guided-Mode Leakage to Control Bound States in the Continuum-Coupled Quantum Dot Emission.

ACS nano·2026
Same author

Point of care molecular cancer diagnostics.

Lab on a chip·2026

Related Experiment Video

Updated: Feb 25, 2026

Author Spotlight: Development of a Smartphone-Enhanced Paper-Based Device for Rapid Dengue NS1 Detection
06:00

Author Spotlight: Development of a Smartphone-Enhanced Paper-Based Device for Rapid Dengue NS1 Detection

Published on: January 26, 2024

2.1K

Multimode smartphone biosensing: the transmission, reflection, and intensity spectral (TRI)-analyzer.

Kenneth D Long1, Elizabeth V Woodburn, Huy M Le

  • 1Department of Bioengineering, Micro and Nano Technology Laboratory, University of Illinois at Urbana-Champaign, 208 N. Wright Street, Urbana, IL 61801, USA. bcunning@illinois.edu.

Lab on a Chip
|July 29, 2017
PubMed
Summary

This study presents a smartphone-based spectrometer for point-of-care diagnostics. The handheld instrument analyzes microfluidic assays for maternal and infant health, achieving lab-comparable detection limits.

More Related Videos

Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum
09:23

Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum

Published on: December 13, 2017

6.7K
Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis
10:35

Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis

Published on: October 17, 2016

8.3K

Related Experiment Videos

Last Updated: Feb 25, 2026

Author Spotlight: Development of a Smartphone-Enhanced Paper-Based Device for Rapid Dengue NS1 Detection
06:00

Author Spotlight: Development of a Smartphone-Enhanced Paper-Based Device for Rapid Dengue NS1 Detection

Published on: January 26, 2024

2.1K
Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum
09:23

Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum

Published on: December 13, 2017

6.7K
Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis
10:35

Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis

Published on: October 17, 2016

8.3K

Area of Science:

  • Biomedical Engineering
  • Spectroscopy
  • Point-of-Care Diagnostics

Background:

  • Conventional laboratory diagnostic equipment is often expensive and inaccessible in point-of-care settings.
  • There is a need for portable, cost-effective analytical instruments for rapid disease detection.

Purpose of the Study:

  • To develop and validate a smartphone-integrated handheld instrument for diverse spectroscopic measurements.
  • To demonstrate the instrument's utility in point-of-care maternal and infant health assays.

Main Methods:

  • Utilized a smartphone camera as a high-resolution spectrometer.
  • Integrated smartphone LED and laser diode for illumination of microfluidic cartridges.
  • Employed optical fibers and a diffraction grating to capture spectral data.
  • Developed software for automated spectral analysis from microfluidic chambers.

Main Results:

  • Successfully measured colorimetric absorption, fluorescence emission, and resonant reflection spectra.
  • Demonstrated comparable limits of detection to laboratory microplate readers for fetal fibronectin and phenylalanine assays.
  • Validated the system for point-of-care (POC) applications in maternal and infant health.

Conclusions:

  • The smartphone-integrated instrument offers a flexible platform for translating existing biosensing assays to POC settings.
  • This technology enables rapid, simple, and accessible diagnostic testing.
  • The system shows significant potential for improving maternal and infant healthcare outcomes.