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Updated: Feb 25, 2026

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A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression

Rajat M Gupta1, Joseph Hadaya2, Aditi Trehan2

  • 1Broad Institute of MIT and Harvard University, Cambridge, MA, USA; Cardiology Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA USA; Center for Genomic Medicine, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

Cell
|July 29, 2017
PubMed

Keywords:
SNPcardiovascular diseasescoronary artery diseaseendothelial cellsendothelin-1epigenomicsgenetic enhancer elementsgenome-wide association studyhypertensionmigraine disorders

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