Recent advances in studying single bacteria and biofilm mechanics
Catherine Even1, Christian Marlière2, Jean-Marc Ghigo3
1Laboratoire de Physique des Solides, Université Paris-Sud, CNRS, Université Paris-Saclay, 91405 Orsay Cedex, France.
Abstract:
Bacterial biofilms correspond to surface-associated bacterial communities embedded in hydrogel-like matrix, in which high cell density, reduced diffusion and physico-chemical heterogeneity play a protective role and induce novel behaviors. In this review, we present recent advances on the understanding of how bacterial mechanical properties, from single cell to high-cell density community, determine biofilm tri-dimensional growth and eventual dispersion and we attempt to draw a parallel between these properties and the mechanical properties of other well-studied hydrogels and living systems.


