Erratum to: Non-invasive measures of coronary microcirculation: Taking the long road to the clinic

Area of Science:

• Nuclear cardiology
• Preclinical imaging research
• Cardiovascular diagnostics

Context:

• Accurate assessment of intramyocardial blood volume (IBV) is crucial for diagnosing and managing cardiac conditions.
• Current methods for IBV quantification may have limitations in precision and accessibility.
• Advancements in nuclear imaging offer potential for improved cardiovascular assessment.

Purpose:

• To evaluate the efficacy of 99mTc-RBC SPECT-CT imaging for precise quantification of intramyocardial blood volume in a preclinical setting.
• To establish a reliable imaging technique for assessing myocardial perfusion and blood volume.

Summary:

• This preclinical study successfully quantified intramyocardial blood volume using 99mTc-RBC SPECT-CT imaging.
• The results indicate that 99mTc-RBC SPECT-CT is a viable method for accurate IBV measurement.
• The study provides a foundation for potential clinical translation of this imaging technique.

Impact:

• This research introduces a novel application of SPECT-CT imaging for cardiovascular assessment.
• The validated method could enhance the diagnostic capabilities for various heart diseases.
• Successful IBV quantification may lead to more personalized treatment strategies in cardiology.