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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Related Experiment Video

Updated: Feb 25, 2026

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
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Keratoconus Treatment Algorithm.

Konstantinos D Andreanos1, Kate Hashemi2, Myrsini Petrelli3

  • 11st Department of Ophthalmology, 'G. Gennimatas Hospital', National and Kapodistrian University of Athens, Athens, Greece. coandre80@icloud.com.

Ophthalmology and Therapy
|July 30, 2017
PubMed
Summary

Recent advancements in keratoconus management offer new treatment options for visual rehabilitation. This review covers current evidence for cornea cross-linking, intrastromal corneal ring segments, and combined therapies.

Keywords:
Accelerated cross-linkingCXL plusCorneal cross-linkingEpi-on cross-linkingIntrastromal corneal ring segmentsKeratoconus treatment algorithm

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Area of Science:

  • Ophthalmology
  • Corneal Science
  • Vision Rehabilitation

Background:

  • Keratoconus is a progressive corneal ectasia affecting vision.
  • Management has evolved significantly in the past 20 years.
  • Traditional treatments are often insufficient for advanced cases.

Purpose of the Study:

  • To review current evidence for novel keratoconus interventions.
  • To highlight the role of new treatments in visual rehabilitation.
  • To discuss emerging therapies for keratoconus.

Main Methods:

  • Systematic review of recent literature.
  • Analysis of clinical evidence for specific treatments.
  • Evaluation of treatment outcomes and safety profiles.

Main Results:

  • Cornea cross-linking demonstrates efficacy in halting keratoconus progression.
  • Intrastromal corneal ring segments improve visual acuity and corneal shape.
  • Combined treatments offer synergistic benefits for visual rehabilitation.

Conclusions:

  • Modern keratoconus management includes effective options like cross-linking and ring segments.
  • These interventions provide significant visual rehabilitation for patients.
  • Ongoing research into novel therapies promises further advancements.