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Updated: Feb 25, 2026

Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking
Published on: November 17, 2023
PRODIGE: PRediction models in prOstate cancer for personalized meDIcine challenGE
A R Alitto1, R Gatta1, Bgl Vanneste2
1Radiation Oncology Area, Gemelli-ART, Catholic University of the Sacred Heart, Rome, Italy.
Aim:
Identifying the best care for a patient can be extremely challenging. To support the creation of multifactorial Decision Support Systems (DSSs), we propose an Umbrella Protocol, focusing on prostate cancer.
Materials & Methods:
The PRODIGE project consisted of a workflow for standardizing data, and procedures, to create a consistent dataset useful to elaborate DSSs. Techniques from classical statistics and machine learning will be adopted. The general protocol accepted by our Ethical Committee can be downloaded from cancerdata.org .
Results:
A standardized knowledge sharing process has been implemented by using a semi-formal ontology for the representation of relevant clinical variables.
Conclusion:
The development of DSSs, based on standardized knowledge, could be a tool to achieve a personalized decision-making.

