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Effectiveness of Human Research Protection Program Performance Measurements.

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Performance measurement significantly improved human research protection programs within the Department of Veterans Affairs. Data from 2010-2016 show 84% of metrics improved, demonstrating the effectiveness of tracking performance for better outcomes.

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Area of Science:

  • Health Services Research
  • Clinical Research Ethics
  • Program Evaluation

Background:

  • Human research protection programs (HRPPs) are crucial for ethical research conduct.
  • Performance metrics are increasingly used to assess and improve HRPP operations.
  • The Department of Veterans Affairs (VA) oversees numerous research facilities with HRPPs.

Purpose of the Study:

  • To evaluate the impact of performance measurement on HRPP effectiveness within the VA.
  • To identify trends in HRPP performance metrics from 2010 to 2016.
  • To determine if performance measurement drives improvements in research protection.

Main Methods:

  • Analysis of HRPP performance metric data from all VA research facilities.
  • Data collected spanned the years 2010 to 2016.
  • Statistical analysis of 25 distinct performance metrics, noting changes and rates of improvement.

Main Results:

  • 84% (21 of 25) of HRPP performance metrics showed improvement between 2010 and 2016.
  • The average improvement across these metrics was 81.1% ± 18.7%.
  • Metrics with initially low noncompliance rates (<1.0%) also demonstrated significant improvement, indicating potential for enhancement even at high performance levels.

Conclusions:

  • Performance measurement is a demonstrably effective strategy for enhancing HRPP performance.
  • Continuous monitoring and evaluation of HRPP metrics can lead to substantial improvements in research protection.
  • The VA's experience suggests that performance measurement systems positively impact ethical research oversight.