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Updated: Feb 25, 2026

Use of the Soft-agar Overlay Technique to Screen for Bacterially Produced Inhibitory Compounds
Published on: January 14, 2017
Evidence for differentiated ionic and surface contact effects driving bacterial inactivation by way of genetically
Sami Rtimi1, Victor Nadtochenko, Inessa Khmel
1Ecole Polytechnique Fédérale de Lausanne, EPFL-SB-ISIC-GPAO, Station 6, CH-1015, Lausanne, Switzerland. sami.rtimi@epfl.ch.
Abstract:
New evidence is presented for the bacterial inactivation of E. coli presenting normal porins on sputtered Ag-Cu surfaces compared with similar E. coli porinless bacteria. Inactivation at a reduced rate was observed on the genetically modified porinless bacteria interacting via surface contact with metal/oxides without the intervention of metal-ions.
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