Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Feb 25, 2026

A Mobile Outside-in Technique of Transforaminal Lumbar Endoscopy for Lumbar Disc Herniations
05:50

A Mobile Outside-in Technique of Transforaminal Lumbar Endoscopy for Lumbar Disc Herniations

Published on: August 7, 2018

12.4K

Keyhole approaches to intradural pathologies.

Klaus C Mende1, Theresa Krätzig1, Malte Mohme1

  • 1Department of Neurosurgery, University Medical Center Hamburg, Germany.

Neurosurgical Focus
|August 2, 2017
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Oncological and neurological outcomes after parent rootlet resection in functionally critical spinal schwannomas: a retrospective multicenter comparative study.

Journal of neurosurgery. Spine·2026
Same author

SENIPERA Phase 0/1 randomized window-of-opportunity clinical trial of SENIcapoc and PERAmpanel mono- and combination therapy of newly diagnosed glioblastoma: a trial protocol.

BMC cancer·2026
Same author

Targeting purinergic receptors in glioblastoma with nanobody-displaying AAV vectors.

Neuropharmacology·2026
Same author

Profiling of rare immune cell populations and integrative analysis identify immune ecotypes in newly diagnosed meningiomas.

Acta neuropathologica communications·2026
Same author

Benign or aggressive? Understanding spinal melanocytomas in comparison to malignant melanoma.

Journal of neuro-oncology·2025
Same author

Training in endoscopic endonasal surgery: EANS young neurosurgeons committee survey.

Neurosurgical review·2025
Same journal

Letter to the Editor. Enhancing comparability in idiopathic intracranial hypertension research through standardized outcome measures.

Neurosurgical focus·2026
Same journal

Introduction. Contemporary spinal arthroplasty.

Neurosurgical focus·2026
Same journal

Cervical disc arthroplasty as a safe and effective procedure for obese patients.

Neurosurgical focus·2026
Same journal

Comparing the operational metrics and functional outcomes of lumbar arthroplasty implants: a systematic review.

Neurosurgical focus·2026
Same journal

Long-term reoperation risk after cervical disc arthroplasty versus fusion: a level-matched meta-analysis of FDA investigational device exemption studies and international randomized trials.

Neurosurgical focus·2026
Same journal

Total disc replacement versus lumbar interbody fusion for degenerative disc disease: a meta-analysis of randomized controlled trials.

Neurosurgical focus·2026
See all related articles

Minimally invasive mini-open approaches enable safe resection of intradural spinal tumors, reducing complications and preserving spinal stability. This technique is effective for meningiomas and neuromas, with selected use for intramedullary tumors.

Area of Science:

  • Neurosurgery
  • Spinal Surgery
  • Oncology

Background:

  • Spinal tumors are rare, comprising 2%-4% of central nervous system tumors.
  • Traditional wide surgical approaches carry risks of complications like skin incisions and spinal instability.
  • Minimally invasive techniques aim to reduce these surgical morbidities.

Purpose of the Study:

  • To evaluate the safety and efficacy of mini-open surgical approaches for intradural spinal tumors.
  • To compare outcomes between mini-open and traditional large exposure approaches.
  • To analyze complications and spinal stability following mini-open tumor resection.

Main Methods:

  • Retrospective review of 245 patients with intramedullary and intradural extramedullary tumors treated between 2009 and 2016.
Keywords:
intraduralkeyholeminimally invasivespine

More Related Videos

Full-Endoscopic Interlaminar Approach for Decompression of Lateral Recess Stenosis
02:02

Full-Endoscopic Interlaminar Approach for Decompression of Lateral Recess Stenosis

Published on: February 24, 2023

1.1K
Intraoperative Ultrasound in Spinal Surgery
05:53

Intraoperative Ultrasound in Spinal Surgery

Published on: August 17, 2022

5.4K

Related Experiment Videos

Last Updated: Feb 25, 2026

A Mobile Outside-in Technique of Transforaminal Lumbar Endoscopy for Lumbar Disc Herniations
05:50

A Mobile Outside-in Technique of Transforaminal Lumbar Endoscopy for Lumbar Disc Herniations

Published on: August 7, 2018

12.4K
Full-Endoscopic Interlaminar Approach for Decompression of Lateral Recess Stenosis
02:02

Full-Endoscopic Interlaminar Approach for Decompression of Lateral Recess Stenosis

Published on: February 24, 2023

1.1K
Intraoperative Ultrasound in Spinal Surgery
05:53

Intraoperative Ultrasound in Spinal Surgery

Published on: August 17, 2022

5.4K
  • Detailed description of the mini-open keyhole/interlaminar surgical technique.
  • Analysis of tumor subgroups (meningioma, neuroma, intramedullary) and associated complications.
  • Main Results:

    • Mini-open approaches successfully resected all meningiomas (n=79) and neuromas (n=72).
    • Only 5.3% of intramedullary tumors were accessed via mini-open techniques, often requiring laminotomy or laminectomy.
    • Surgery-associated complications were significantly lower in the mini-open group (9.6%) compared to the large exposure group (19.1%).

    Conclusions:

    • Mini-open interlaminar approaches are safe and effective for resecting intradural extramedullary spinal tumors.
    • This technique preserves spinal stability and reduces comorbidities by avoiding extensive laminectomies.
    • Selected intramedullary pathologies can also be addressed with this minimally invasive method.