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Updated: Feb 25, 2026

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens
Published on: April 18, 2013
Successful desensitization to radiocontrast media in two high-risk cardiac patients
Mona Al-Ahmad1, Tito Rodriguez Bouza
1Mona Al-Ahmad, Department of Microbiology,, Faculty of Medicine, Kuwait University,, PO Box 24923,, Safat 13110, Kuwait, T: +965-24636515, F: +965-25332719, Alahmadm@hsc.edu.kw, ORCID: orcid.org/0000-0003-3720-7032.
Abstract:
Hypersensitivity reactions to radiocontrast media (RCM) are common and in severe cases may present a challenge for treating physician in cases when premedication fails or the patient presents with severe comorbidities. We describe two cases in need of radiocontrast media after a severe reaction on previous exposure to iohexol. One presented anaphylactic reaction to RCM despite premedication and another presented with angina. Both cases were treated with a desensitization protocol to iodixanol. In conclusion, desensitization to radiocontrast media may be considered in patients with previously unsuccessful premedication and/or severe acute comorbidities.
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