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Three Cases of Autoimmune Progesterone Dermatitis
Hye Rin You1, Sook Jung Yun1, Sung Jin Kim1
1Department of Dermatology, Chonnam National University Medical School, Gwangju, Korea.
Annals of Dermatology
|August 2, 2017
Summary
Autoimmune progesterone dermatitis is a rare cyclic skin condition. Early diagnosis through menstrual history and intradermal testing is crucial for managing these monthly eruptions.
Area of Science:
- Dermatology
- Endocrinology
- Immunology
Background:
- Autoimmune progesterone dermatitis is a rare condition characterized by cyclic premenstrual skin reactions.
- Symptoms often mimic other dermatoses like eczema and urticaria, leading to potential misdiagnosis.
Observation:
- Three cases of autoimmune progesterone dermatitis are presented, all with recurrent monthly skin eruptions preceding menstruation.
- Clinical presentations varied, including erythema annulare centrifugum, urticaria, contact dermatitis, and rosacea.
Findings:
- Diagnosis was confirmed via intradermal progesterone testing.
- Variable clinical manifestations can lead to misdiagnosis if not carefully evaluated.
Implications:
- Dermatologists should consider autoimmune progesterone dermatitis in women with cyclic eruptions.
- Thorough history, including menstrual cycle details, and intradermal progesterone testing are recommended for suspected cases.
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