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Recurrent intraventricular meningioma with malignant transformation
Jasmit Singh1, Hrushikesh Kharosekar1, Vernon Velho1
1Department of Neurosurgery, Grant Medical College, Mumbai, Maharashtra, India.
Asian Journal of Neurosurgery
|August 2, 2017
Summary
This case report details the first known instance of a benign intraventricular meningioma transforming into a chondrosarcoma. This rare malignant transformation highlights unusual tumor progression in the brain.
Area of Science:
- Neuro-oncology
- Pathology
- Neurosurgery
Background:
- Meningiomas are common primary brain tumors, typically benign.
- Intraventricular meningiomas represent a small subset of these tumors.
- Malignant transformation of meningiomas is infrequent.
Observation:
- A rare case of a benign intraventricular meningioma was observed.
- The tumor exhibited a transformation into a chondrosarcoma.
- This represents a highly unusual location and type of malignant progression.
Findings:
- This is the first reported case of benign intraventricular meningioma progressing to chondrosarcoma.
- The case highlights the potential for aggressive behavior even in intraventricular meningiomas.
- Histopathological analysis confirmed the malignant transformation.
Implications:
- This case expands the understanding of meningioma behavior and potential for dedifferentiation.
- It underscores the importance of vigilant monitoring and considering malignant transformation in intraventricular meningiomas.
- Further research into the mechanisms of meningioma malignant transformation is warranted.
