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Updated: Feb 25, 2026

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Published on: June 8, 2022
Minocycline induced lupus with yellow colored chylous exudative pleural effusion
Daniel Starobin1, Vladimir Guller2, Alexander Gurevich3
1Pulmonary Institute, Kaplan Medical Center, Affiliated with The Hebrew University of Jerusalem, Israel, Rehovot, Israel.
Abstract:
Ninety years old male was admitted to hospital due to breathlessness. The prominent findings were extensive blue-grey skin pigmentation and large left chylothorax. Drug induced lupus was diagnosed due to either minocycline chronic treatment or no alternative illness to explain his sub-acute disease. Minocycline therapy was stopped with gradual improvement of pleural effusion and skin discoloration. This case is the first presentation of minocycline induced lupus with chylothorax.
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