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Updated: Feb 25, 2026

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Published on: August 30, 2022
Severe aortic regurgitation complicating Takayasu's arteritis
Wala M Alali1, Saeed A Alahmari, Yahya S Alhebaishi
1Department of Internal Medicine, Prince Sultan Military Medical City, Riyadh, Kingdom of Saudi Arabia. E-mail:. wala.alali@hotmail.com.
Takayasu arteritis (TA) can cause severe aortic regurgitation and ascending aortic aneurysms. Corticosteroid treatment managed this rare cardiac presentation, delaying surgery.
Area of Science:
- Cardiology
- Vascular Surgery
- Rheumatology
Background:
- Takayasu arteritis (TA) is a rare, chronic inflammatory disease affecting large arteries, primarily the aorta and its branches.
- Cardiac manifestations of TA can be diverse, including valvular disease and aortic aneurysms.
Observation:
- A 48-year-old female presented with severe aortic regurgitation, ascending aortic aneurysm, and dyspnea.
- Imaging revealed complete occlusion of the right carotid artery, stenosis of left subclavian and vertebral arteries, and a right subclavian artery aneurysm.
Findings:
- Takayasu arteritis was identified as the underlying cause of the patient's complex cardiovascular pathology.
- Computed tomography and cardiac MRI provided detailed anatomical insights into the arterial involvement.
Implications:
- This case highlights the importance of considering Takayasu arteritis in patients with atypical cardiac symptoms and valvular involvement.
- Early diagnosis and management with corticosteroids can potentially avert immediate surgical intervention in selected cases.
Related Concept Videos
Aortic Regurgitation I: Introduction
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Aortic Regurgitation III: Medical Management
Aortic Regurgitation IV: Nursing Management
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Rheumatic Heart Disease I: Introduction

