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Gastro-Esophageal Reflux in Children

Anna Rybak1, Marcella Pesce2,3, Nikhil Thapar4,5

  • 1Department of Gastroenterology, Division of Neurogastroenterology and Motility, Great Ormond Street Hospital, London WC1N 3JH, UK. anna.rybak@gosh.nhs.uk.

International Journal of Molecular Sciences
|August 2, 2017
PubMed

Insights

Gastro-esophageal reflux disease (GERD) in infants and children presents differently than in adults. This review covers GERD

Area of Science:

  • Pediatrics
  • Gastroenterology

Background:

  • Gastro-esophageal reflux (GER) is common in infants and children.
  • GER can range from benign regurgitation to severe complications defining pathological GERD.
  • Infant GERD symptoms often differ from adult presentations like heartburn.

Purpose of the Study:

  • To review the presentation, diagnosis, and treatment of GERD in infants and children.
  • To provide guidance based on current clinical guidelines.

Main Methods:

  • Literature review of current guidelines and available data on pediatric GERD.
  • Focus on clinical presentation, diagnostic approaches, and therapeutic strategies.

Main Results:

  • Infants have unique factors exacerbating GER, including diet, position, and immature gastro-esophageal junction.
  • GERD presentation in children is distinct from adult symptomatology.
  • Guidelines offer a framework for managing pediatric GERD.

Conclusions:

  • Understanding the distinct features of GERD in infants and children is crucial for accurate diagnosis and management.
  • Current guidelines provide a basis for effective treatment strategies.
  • Further research may refine management protocols for pediatric GERD.

Keywords:
childrenextraintestinal symptomsgastro-esophageal refluxguidelinesinfants

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