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Updated: Feb 25, 2026

Author Spotlight: Assessing the Cardiovascular Profile of Patients with Metabolic Syndrome
Published on: September 27, 2024
[Myocardial infarction in young mexicans associated to metabolic syndrome]
Álvaro Mathiew-Quirós1, Ana María Salinas-Martínez1, Francisco Javier Guzmán de la Garza1
1Unidad de Investigación Epidemiológica y en Servicios de Salud, Monterrey, N.L., México.
Background:
Acute coronary diseases are catastrophic, especially in young patients.
Objective:
To determine the risk of metabolic syndrome (MS) for premature acute myocardial infarction (AMI), combined with familial, behavioral, and nutritional factors in the northeast of Mexico.
Material And Methods:
This is a case control study of patients less than 47 years of age with no personal history of angina, AMI, or cerebrovascular disease. Cases corresponded to patients with AMI (incident and primary cases; n = 55) and controls were blood donors located at the same hospital (n = 55). Behavioral, nutritional, and cardiometabolic risk factors were measured. Multivariate logistic regression was used for estimating odds ratios (OR) and 95% confidence intervals (95% CI).
Results:
MS increased the risk for premature AMI (95% CI: 1.73-39.5) eightfold, followed by smoking (OR: 7.76; 95% CI: 1.27-47.3), family history of AMI or sudden death (OR: 11.0; 95% CI: 2.03-60.4), and sedentary lifestyle (OR: 2.26; 95% CI: 2.52-9.80), independent of potential confounders.
Conclusions:
The study highlights the magnitude of the risk of MS for AMI in Mexican young adults. The phenomenon of coronary diseases among young adults needs essential attention from the health sector.
Insights
Metabolic syndrome (MS) significantly increases the risk of premature acute myocardial infarction (AMI) in young Mexican adults. Other key risk factors include smoking, family history, and sedentary lifestyle.
Area of Science:
- Cardiology
- Metabolic Disorders
- Public Health
Background:
- Acute coronary diseases pose a severe threat, particularly to younger populations.
- Premature acute myocardial infarction (AMI) in young individuals is a critical health concern.
Purpose of the Study:
- To investigate the association between metabolic syndrome (MS) and premature AMI in Northeast Mexico.
- To identify familial, behavioral, and nutritional factors contributing to premature AMI risk.
Main Methods:
- A case-control study involving 55 patients with premature AMI and 55 healthy blood donors under 47 years old.
- Assessment of behavioral, nutritional, and cardiometabolic risk factors.
- Multivariate logistic regression analysis to determine odds ratios (OR) and 95% confidence intervals (95% CI).
Main Results:
- Metabolic syndrome (MS) was associated with an eightfold increased risk of premature AMI.
- Smoking (OR: 7.76) and a family history of AMI or sudden death (OR: 11.0) were significant risk factors.
- Sedentary lifestyle also increased the risk (OR: 2.26), independent of other factors.
Conclusions:
- Metabolic syndrome poses a substantial risk for AMI in young Mexican adults.
- Coronary heart disease in young people requires urgent attention from healthcare systems.
- Early identification and management of MS are crucial for preventing premature AMI.
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