[Myocardial infarction in young mexicans associated to metabolic syndrome]

Álvaro Mathiew-Quirós1, Ana María Salinas-Martínez1, Francisco Javier Guzmán de la Garza1

  • 1Unidad de Investigación Epidemiológica y en Servicios de Salud, Monterrey, N.L., México.

Gaceta Medica De Mexico
|August 2, 2017
PubMed
Abstract

Insights

Metabolic syndrome (MS) significantly increases the risk of premature acute myocardial infarction (AMI) in young Mexican adults. Other key risk factors include smoking, family history, and sedentary lifestyle.

Area of Science:

  • Cardiology
  • Metabolic Disorders
  • Public Health

Background:

  • Acute coronary diseases pose a severe threat, particularly to younger populations.
  • Premature acute myocardial infarction (AMI) in young individuals is a critical health concern.

Purpose of the Study:

  • To investigate the association between metabolic syndrome (MS) and premature AMI in Northeast Mexico.
  • To identify familial, behavioral, and nutritional factors contributing to premature AMI risk.

Main Methods:

  • A case-control study involving 55 patients with premature AMI and 55 healthy blood donors under 47 years old.
  • Assessment of behavioral, nutritional, and cardiometabolic risk factors.
  • Multivariate logistic regression analysis to determine odds ratios (OR) and 95% confidence intervals (95% CI).

Main Results:

  • Metabolic syndrome (MS) was associated with an eightfold increased risk of premature AMI.
  • Smoking (OR: 7.76) and a family history of AMI or sudden death (OR: 11.0) were significant risk factors.
  • Sedentary lifestyle also increased the risk (OR: 2.26), independent of other factors.

Conclusions:

  • Metabolic syndrome poses a substantial risk for AMI in young Mexican adults.
  • Coronary heart disease in young people requires urgent attention from healthcare systems.
  • Early identification and management of MS are crucial for preventing premature AMI.

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