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Related Concept Videos

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The presence of a dielectric medium in a capacitor not only changes the voltage and capacitance but also affects the electric field. In general, dielectrics can be of two types: polar and nonpolar. In a polar dielectric, the positive and negative charges in the molecules are separated by a distance and hence have a permanent dipole moment. In contrast, no such charge separation exists in a nonpolar dielectric, however the nonpolar molecules get polarized in the presence of an external electric...
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Electrophoresis is a powerful analytical separation technique that relies on the differential migration of charged species when subjected to an electric field. The core strength of electrophoresis lies in its ability to separate high-molecular-weight species in complex mixtures. It has found widespread use in biochemistry, molecular biology, and analytical chemistry, allowing the separation of compounds like amino acids, nucleotides, carbohydrates, and proteins with excellent resolution.
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Consider a polar dielectric placed in an external field. In such a dielectric, opposite charges on adjacent dipoles neutralize each other, such that the net charge within the dielectric is zero. When a polar dielectric is inserted in between the capacitor plates, an electric field is generated due to the presence of net charges near the edge of the dielectric and the metal plates interface. Since the external electrical field merely aligns the dipoles, the dielectric as a whole is neutral. An...
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Label-free Isolation and Enrichment of Cells Through Contactless Dielectrophoresis
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Nonlinear electrokinetic effects in insulator-based dielectrophoretic systems.

Qianru Wang1, Naga Neehar Dingari1, Cullen R Buie1

  • 1Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.

Electrophoresis
|August 2, 2017
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Summary

Insulator-based dielectrophoresis (iDEP) uses electric fields to manipulate fluids in microchannels. This study reveals how electrothermal and induced charge electroosmosis flows interact, impacting cell separation and concentration in iDEP systems.

Keywords:
ElectrokineticElectrothermalInduced charge electroosmosisInsulator-based dielectrophoresisJoule heating

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Area of Science:

  • Biomicrofluidics
  • Electrokinetics
  • Microfluidic device design

Background:

  • Insulator-based dielectrophoresis (iDEP) is vital for microfluidic applications like cell manipulation.
  • iDEP relies on electric field gradients generated by altered microchannel geometries.
  • AC electric fields induce nonlinear electrokinetic phenomena affecting fluid flow.

Purpose of the Study:

  • Investigate the interplay between electrothermal flow and induced charge electroosmosis (ICEO) in iDEP.
  • Analyze the influence of microchannel geometry and fluid ionic strength on these flows.
  • Provide insights for optimizing iDEP system design.

Main Methods:

  • Experimental measurements of temperature rise and fluid velocity.
  • Analytical estimations and numerical simulations of flow dynamics.
  • Study of 2D Gaussian-shaped and 3D microchannel constrictions.

Main Results:

  • Demonstrated distinct recirculating flow patterns in 2D and 3D constrictions.
  • Quantified the interplay of electrothermal and ICEO flows.
  • Developed approximate analytical expressions for velocity scales.

Conclusions:

  • Understanding the interaction of electrothermal and ICEO flows is crucial for iDEP performance.
  • Microchannel geometry and electrolyte concentration significantly influence flow behavior.
  • This research aids in designing more effective microfluidic systems for electrokinetic particle manipulation.